CXCL9 (MIG), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CXCL9 (MIG), Mouse |
| Clone | REA365 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | phycoerythrin (PE) conjugate |
| Size | 30 µg in 1 mL |
| Concentration | 1:10 |
| Applications | Intracellular flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CXCL9 (MIG) Antibody, anti-mouse, PE, REAfinity™. Clone REA365 recognizes the mouse C-X-C motif chemokine ligand 9 (CXCL9) antigen, a small cytokine belonging to the CXC chemokine family that is also known as Monokine induced by interferon γ (MIG). CXCL9 is a T-cell chemoattractant, which is induced by IFN-γ during infection, injury or immunoinflammatory responses in macrophages, hepatocytes, and endothelial cells. It is best known for its role in leucocyte trafficking, principally acting on activated CD4+ Th1 cells, CD8+ T cells and NK cells. CXCL9 also has angiostatic properties. Overexpression of CXCL9 in tumors can lead to T-cell accumulation, vascular damage, and tumor regression. It elicits its chemotactic functions by interacting with the chemokine receptor CXCR3. | Additional information: Clone REA365 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | CMK, γ-interferon-induced monokine, MuMIG, Scyb9, crg-10, MIG |
| Gene, Accession # | Gene ID: 17329 |
| Catalog # | 130-105-148 |
| Price | $66 |
| Order / More Info | CXCL9 (MIG), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Giegold, O. et al. (2013) CXCL9 causes heterologous desensitization of CXCL12-mediated memory T lymphocyte activation. J Immunol 190 (7): 3696-3705. | Kastenmuller, W. et al. (2013) Peripheral prepositioning and local CXCL9 chemokine-mediated guidance orchestrate rapid memory CD8+ T cell responses in the lymph node. Immunity 38 (3): 502-513. | Farber, J. M. et al. (1990) A macrophage mRNA selectively induced by gamma-interferon encodes a member of the platelet factor 4 family of cytokines. Proc. Natl. Acad. Sci. U.S.A. 87 (14): 5238-5242. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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