CD117, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD117, Mouse |
| Clone | REA791 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | Vio Bright B515 conjugate |
| Size | 150 µg in 1 mL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD117 Antibody, anti-mouse, Vio® Bright B515, REAfinity™. Clone REA791 recognizes the mouse CD117 antigen, a 145 kDa cell surface glycoprotein belonging to the class III receptor tyrosine kinase family. CD117 is also known as c-kit or stem cell factor (SCF) receptor. It is expressed on the majority of hematopoietic progenitor cells including multipotent hematopoietic stem cells as well as some committed myeloid, erythroid and lymphoid precursor cells, and mature mast cells. CD117+ stem cells from murine bone marrow could also be differentiated into smooth muscle cells, myocytes, and endothelial cells in vivo. | Additional information: Clone REA791 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | c-kit, SCO1, SCO5, SOW3, Ssm, Tr-kit, KIT, W, SCFR |
| Gene, Accession # | Gene ID: 16590 |
| Catalog # | 130-111-618 |
| Price | $625 |
| Order / More Info | CD117, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Qiu, F. H. et al. (1998) Primary structure of c-kit: relationship with the CSF-1/PDGF receptor kinase family--oncogenic activation of v-kit involves deletion of extracellular domain and C terminus. EMBO J. 7 (4): 1003-1011. | Orlic, D. (2002) Stem cell repair in ischemic heart disease: an experimental model. Int. J. Hematol. 76 (suppl.1): 144-145. | Zayas, J. et al. (2008) Murine hematopoietic stem cells and multipotent progenitors express truncated intracellular form of c-kit receptor. Stem Cells Dev. 17 (2): 343-353. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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