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Antigenic Specificity | CD134 (OX40), Mouse |
Clone | OX-86 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG1κ |
Format | phycoerythrin (PE) conjugate |
Size | 30 µg in 1 mL |
Concentration | 1:10 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD134 (OX40) Antibody, anti-mouse, PE. The CD134 antigen, also known as OX40 receptor, is a 50 kDa type I membrane glycoprotein of the TNF/NGF receptor superfamily. It is expressed on activated mouse T cells and B cells. The OX40 receptor binds to the OX40 ligand (CD252) to provide a costimulatory signal which is independent of CD28. The OX-86 monoclonal antibody does not block this interaction and is reported to provide costimulation signals to T cells. |
Immunogen | n/a |
Other Names | TNFRSF4, TNFRSF4, Ly-70, OX-40, Txgp1l, Txgp1, ACT35 |
Gene, Accession # | Gene ID: 22163 |
Catalog # | 130-102-572 |
Price | $66 |
Order / More Info | CD134 (OX40), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Akiba, H. et al. (1999) CD28-independent costimulation of T cells by OX40 ligand and CD70 on activated B cells. J Immunol 162 (12): 7058-7066. | Kjaergaard, J. et al. (2001) Augmentation versus inhibition: effects of conjunctional OX-40 receptor monoclonal antibody and IL-2 treatment on adoptive immunotherapy of advanced tumor. J Immunol 167: 6669-6677. | al-Shamkhani, A. et al. (1996) OX40 is differentially expressed on activated rat and mouse T cells and is the sole receptor for the OX40 ligand. Eur. J. Immunol. 26 (8): 1695-1699. |