SUSD2, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificitySUSD2, Human
CloneW5C5
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1κ
Formatphycoerythrin (PE) conjugate
Size100 tests in 200 µL
Concentration1:50
ApplicationsFlow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
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DescriptionSUSD2 Antibody, anti-human, PE. Clone W5C5 recognizes the human sushi domain-containing protein 2 (SUSD2) antigen, a single-pass type I membrane protein which is expressed by bone marrow mesenchymal stem cells (MSCs), vessel-surrounding smooth muscle cells, and a few neoplastic cell lines. MSCs are multipotent stromal cells in various adult tissues that can replicate as undifferentiated cells and that have the potential to differentiate to lineages of mesenchymal tissues, including bone, cartilage, fat, tendon, muscle, and marrow stroma. Their application in numerous cases demonstrate their potential in the regeneration of all skeletal tissues, as well as of soft tissue organs. One particular advantage of MSCs is that they can be used when cells from the target tissue for regeneration are not available. SUSD2 expressing cells reside predominantly in a perivascular location in both basal and functional layers of endometrium. They are able to differentiate into adipocytes, osteocytes, chondrocytes, myocytes, and endothelial cells. SUSD2 is a single marker capable of purifying MSC and reconstituting endometrial stromal tissues in vivo. |
Immunogenn/a
Other NamesBK65A6.2, MSC, W5C5
Gene, Accession #Gene ID: 56241
Catalog #130-117-682
Price$315
Order / More InfoSUSD2, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesMasuda, H. et al. (2012) A novel marker of human endometrial mesenchymal stem-like cells. Cell Transplant 21 (10): 2201-2214. | Ulrich, D. et al. (2014) Mesenchymal stem/stromal cells in post-menopausal endometrium. Hum. Reprod. 29 (9): 1895-1905. | Benz, K. et al. (2013) Maintenance of "stem cell" features of cartilage cell sub-populations during in vitro propagation. J. Transl. Med. 11: 27.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

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