CD277, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD277, Human |
| Clone | BT3.1 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1κ |
| Format | biotin conjugate |
| Size | 30 tests in 300 µL |
| Concentration | 1:11 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD277 Antibody, anti-human, Biotin. Clone BT3.1 recognizes the human CD277 antigen, a single-pass type I membrane protein, which is also known as butyrophilin subfamily 3 member A1 (BTN3A1). CD277 belongs to the B7 family members and is expressed in various immune cells such as T cells, B cells, monocytes, NK cells, dendritic cells, a subset of stem cells, and endothelial cells. It is also consistently expressed in stromal and some tumor cells. CD277 triggering considerably enhances T cell receptor (TCR) induced cytokine production and cell proliferation. It mediates the response of T cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate. |
| Immunogen | n/a |
| Other Names | BTN3A1, BTF5, BT3.1, BTN3.1, BTN3A2, BT3.2, BTF4, BTN3.2 |
| Gene, Accession # | Gene ID: 11119 |
| Catalog # | 130-108-247 |
| Price | $110 |
| Order / More Info | CD277, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Messal, N. et al. (2011) Differential role for CD277 as a co-regulator of the immune signal in T and NK cells. Eur. J. Immunol. 41 (12): 3443-3454. | Tazi-Ahnini, R. et al. (1997) Cloning, localization, and structure of new members of the butyrophilin gene family in the juxta-telomeric region of the major histocompatibility complex. Immunogenetics 47 (1): 55-63. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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