CD20L (MS4A3), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityCD20L (MS4A3), Human
CloneREA756
Host SpeciesRecombinant Human
Reactive Specieshuman
IsotypeIgG1
FormatPE-Vio 770 conjugate
Size30 tests in 60 µL
Concentration1:50
ApplicationsIntracellular flow cytometry
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DescriptionCD20L (MS4A3) Antibody, anti-human, PE-Vio® 770, REAfinity™. Clone REA756 recognizes the human CD20L, an intracytoplasmic membrane protein, which is also known as Htm4 or MS4A3. It is present specifically in hematopoietic cells and tissues. CD20L functions as a hematopoietic modulator for the G1-S cell cycle transition. It binds to cyclin-dependent kinase inhibitor 3 (CDKN3/KAP) and modulates the level of phosphorylation of cyclin-dependent kinase 2 (CDK2). | Additional information: Clone REA756 displays negligible binding to Fc receptors.
Immunogenn/a
Other NamesCD20L, HTM4
Gene, Accession #Gene ID: 932
Catalog #130-110-856
Price$162
Order / More InfoCD20L (MS4A3), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesDonato, J. L. et al. (2002) Human HTm4 is a hematopoietic cell cycle regulator. J. Clin. Invest. 109 (1): 51-58. | Chinami, M. et al. (2005) Binding of HTm4 to cyclin-dependent kinase (Cdk)-associated phosphatase (KAP).Cdk2.cyclin A complex enhances the phosphatase activity of KAP, dissociates cyclin A, and facilitates KAP dephosphorylation of Cdk2. J. Biol. Chem. 280 (17): 17235-17242.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

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