CD61, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD61, Human |
| Clone | REA761 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | PE-Vio 615 conjugate |
| Size | 30 tests in 60 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD61 Antibody, anti-human, PE-Vio® 615, REAfinity™. Clone REA761 recognizes the human CD61 antigen, a cell surface protein belonging to the integrin family. CD61 is also known as the integrin β3-subunit. It associates with CD41 to form the heterodimeric gpIIb/gpIIIa complex that is present on human megakaryocytes and platelets and mediates cell adhesion processes. Together with CD51, CD61 forms the vitronectin receptor, which is present on platelets as well as on a variety of other cell types such as osteoclasts and endothelial vessel cells. Clone REA761 specifically recognizes the integrin β3-chain of both heterodimeric complexes. | Additional information: Clone REA761 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | ITGB3, BDPLT16, BDPLT2, GP3A, GPIIIa, GT |
| Gene, Accession # | Gene ID: 3690 |
| Catalog # | 130-110-893 |
| Price | $162 |
| Order / More Info | CD61, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Naik, U. P. et al. (1997) Identification of a novel calcium-binding protein that interacts with the integrin alphaIIb cytoplasmic domain. J. Biol. Chem. 272 (8): 4651-4654. | Kumar, C. S. et al. (1997) Cloning and characterization of a novel integrin beta3 subunit. J. Biol. Chem. 272 (26): 16390-16397. | Hynes, R. O. (2002) Integrins: bidirectional, allosteric signaling machines. Cell 110 (6): 673-687. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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