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Antigenic Specificity | CD66ace, Human |
Clone | REA889 |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | IgG1 |
Format | Vio Bright V423 conjugate |
Size | 30 tests in 60 µL |
Concentration | 1:50 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD66ace Antibody, anti-human, Vio® Bright V423, REAfinity™. Clone REA889 recognizes the a, c, and e epitopes of the human CD66 antigen. CD66 constitutes a gene family whose members belong to the Ig superfamily of carcinoembryonic antigens (CEA). They are involved in a wide variety of physiological processes such as embryonic development, pregnancy, bile transport, as well as pathological conditions such as cancer, bacterial or viral infection, and inflammation. CD66a (CEACAM1), CD66c (CEACAM6), and CD66e (CEACAM5) are differentially expressed on some epithelial cells as well as on T cells, NK cell subsets, and granulocytes, especially neutrophils. | Additional information: Clone REA889 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | CEACAM1, CEACAM5, CEACAM6 |
Gene, Accession # | Gene ID: 634, 1048, 468 |
Catalog # | 130-128-655 |
Price | $208 |
Order / More Info | CD66ace, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Gray-Owen, S. D. and Blumberg, R. S. (2006) CEACAM1: contact-dependent control of immunity. Nat. Rev. Immunol. 6: 433-446. | Guillaume, N. et al. (2011) CD66c expression in B-cell acute lymphoblastic leukemia: strength and weakness. Int J Lab Hematol 33 (1): 92-96. |