IL-17A, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | IL-17A, Mouse |
| Clone | TC11-18H10 |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgG1κ |
| Format | fluorescein (FITC) conjugate |
| Size | 9 µg in 300 µL |
| Concentration | 1:10 |
| Applications | Intracellular flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | IL-17A Antibody, anti-mouse, FITC. The Anti-IL-17A antibodies are designed for intracellular staining of IL-17A-producing cells. | Interleukin 17 (IL-17) is a family of cytokines that play a central role in adaptive immunity as well as autoinflammatory disorders. 1) Data from several mouse models suggest that IL-17 plays a key role in the host defense against certain extracellular bacterial infections. | Recently, a new mouse T helper cell subset has been identified, which is distinct from Th1 and Th2 cells: IL-17-producing CD4+ T helper (Th17) cells. Th17 cells preferentially produce IL-17A, IL-17F, IL-21, and IL-22. Receptors for IL-17 and IL-22 are expressed on various epithelial tissues, thus Th17 cells are crucial for the cross-talk between immune system and tissues. 2) It is now established that Th17 cells are responsible for driving autoimmune inflammation. | After stimulation of mouse T cells, IL-17 is not only secreted by CD4+ T cells, but also by CD8+ T cells and γδ T cells. |
| Immunogen | n/a |
| Other Names | CTLA-8, IL-17 |
| Gene, Accession # | Gene ID: 16171 |
| Catalog # | 130-103-007 |
| Price | $31 |
| Order / More Info | IL-17A, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Ouyang, W. et al. (2008) The biological functions of T helper 17 cell effector cytokines in inflammation. Immunity 28: 454-467. | Weaver, C. T. et al. (2007) IL-17 family cytokines and the expanding diversity of effector T cell lineages. Annu. Rev. Immunol. 25: 821-852. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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