SIT1, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | SIT1, Human |
| Clone | REA864 |
| Host Species | Recombinant Human |
| Reactive Species | human, mouse |
| Isotype | IgG1 |
| Format | allophycocyanin (APC) conjugate |
| Size | 100 tests in 200 µL |
| Concentration | 1:50 |
| Applications | Intracellular flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | SIT1 Antibody, anti-human, APC, REAfinity™. Clone REA864 recognizes the human SIT1 antigen, a disulfide-linked homodimeric glycoprotein also known as SHP2 interacting transmembrane adaptor protein or suppression-inducing transmembrane adapter 1. SIT1 is expressed in lymphocytes and predominantly found in T and B cells as well as in plasma cells. | SIT1 plays a regulatory role in T cell activation and development. In association with Grb2 and SHP2, it is involved in signal transduction. | Additional information: Clone REA864 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | SIT |
| Gene, Accession # | Gene ID: 27240 |
| Catalog # | 130-114-287 |
| Price | $325 |
| Order / More Info | SIT1, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Marie-Cardine, A. et al. (1999) SHP2-interacting transmembrane adaptor protein (SIT), a novel disulfide-linked dimer regulating human T cell activation. J. Exp. Med. 189 (8): 1181-1194. | Tedoldi, S. et al. (2006) Transmembrane adaptor molecules: a new category of lymphoid-cell markers. Blood 107 (1): 213-221. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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