IL-1β, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | IL-1β, Human |
| Clone | REA1172 |
| Host Species | Recombinant Human |
| Reactive Species | human, nonhuman primate |
| Isotype | IgG1 |
| Format | Vio B515 conjugate |
| Size | 30 tests in 60 µL |
| Concentration | 1:50 |
| Applications | Intracellular flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | IL-1β Antibody, anti-human, Vio® B515, REAfinity™. Clone REA1172 recognizes the human IL-1β protein, a proinflammatory cytokine which belongs to the interleukin 1 (IL-1) family. IL-1β is primarly produced by macrophages, but also by monocytes and dendritic cells. It is secreted as a proprotein, that is cleaved by cytosolic caspase 1 (interleukin 1 beta convertase/CASP1/ICE) to form mature IL-1β. It plays an essential role in inflammatory response, promotes cell differentiation, e.g. T?17 differentiation of T cells, and is involved in other cellular activities, including apoptosis. | Additional information: Clone REA1172 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | IL-1beta, IL-1B, IL1B, IL1F2 |
| Gene, Accession # | Gene ID: 3553 |
| Catalog # | 130-120-957 |
| Price | $154 |
| Order / More Info | IL-1β, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Van Damme, J. et al. (1985) Homogeneous interferon-inducing 22K factor is related to endogenous pyrogen and interleukin-1. Nature 314 (6008): 266-268. | Zsebo, K. M. et al. (1988) Effects of hematopoietin-1 and interleukin 1 activities on early hematopoietic cells of the bone marrow. Blood 71 (4): 962-968. | Lukens, J. R. et al. (2014) Dietary modulation of the microbiome affects autoinflammatory disease. Nature 516 (7530): 246-249. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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