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Antigenic Specificity | CD8, Human |
Clone | BW135/80 Fab |
Host Species | n/a |
Reactive Species | human, nonhuman primate |
Isotype | n/a |
Format | phycoerythrin (PE) conjugate |
Size | 30 tests in 60 µL |
Concentration | 1:50 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD8 Antibody, anti-human, PE. Clone BW135/80 Fab recognizes the human CD8 antigen which is strongly expressed on human cytotoxic T cells and thymocytes, and is also expressed on a subset of NK cells. The CD8 antigen is a disulfide-linked dimer that exists either as a CD8α homodimer or as a CD8α/β heterodimer. CD8 acts as a co-receptor for the T cell receptor and binds to the MHC class I molecule. The CD8 antibody recognizes the α-subunit of the antigen. Clone BW135/80 Fab is a clone BW135/80-derived Fab fragment of the full antibody molecule. | Additional information: Clone BW135/80 Fab displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | Leu-2, Ly-2, CD8a, MAL, p32, Cd8b1, LY3, Lyt3, P37, CD8b |
Gene, Accession # | Gene ID: 925 |
Catalog # | 130-125-881 |
Price | $119 |
Order / More Info | CD8, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Jonker, M. et al. (1989) Reactivity of mAb specific for human CD markers with rhesus monkey leucocytes. Oxford, Oxford University Press (Leukocyte Typing IV): 1058-1063. |