CX3CR1, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Search, find, compare suppliers for anti-CX3CR1, Human antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | CX3CR1, Human |
| Clone | REA385 |
| Host Species | Recombinant Human |
| Reactive Species | human, nonhuman primate |
| Isotype | IgG1 |
| Format | Vio Bright V423 conjugate |
| Size | 30 tests in 60 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CX3CR1 Antibody, anti-human, Vio® Bright V423, REAfinity™. Clone REA385 recognizes the human CX3C chemokine receptor 1 antigen, a 40 kDa G-protein-coupled multi-pass membrane protein also known as fractalkine receptor. CX3CR1 is expressed on natural killer (NK) cells, T cell subsets, monocytes/macrophages, dendritic cells (DCs), and some malignant epithelial cells. Binding of CX3CR1 to the membrane-bound form of the chemokine CX3CL1 promotes cell-cell adhesion, whereas the soluble form induces cell migration of CX3CR1-bearing cells such as monocytes, NK cells, T cells, DCs, and macrophages including microglia. CX3CR1 plays also an important role in the formation of transepithelial dendrites by intestinal DCs. Failure in the CX3CL1/CX3CR1 interaction may contribute to the development of several inflammatory diseases including atherosclerosis, psoriasis, rheumatoid arthritis, and experimental autoimmune myositis. | Additional information: Clone REA385 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | CCRL1, CMKBRL1, CMKDR1, GPR13, GPRV28, V28, GPRV28, RBS11 |
| Gene, Accession # | Gene ID: 1524 |
| Catalog # | 130-130-931 |
| Price | $208 |
| Order / More Info | CX3CR1, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Niess, J. H. et al. (2005) CX3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearance. Science 307: 254-258. | Imai, T. et al. (1997) Identification and molecular characterization of fractalkine receptor CX3CR1, which mediates both leukocyte migration and adhesion. Cell 91: 521-530. | Raport, C. J. et al. (1995) The orphan G-protein-coupled receptor-encoding gene V28 is closely related to genes for chemokine receptors and is expressed in lymphoid and neural tissues. Gene 163 (2): 295-299. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
Profile of MILTENYI BIOTEC B.V. & Co. KG
Return to Antibodies