TRA-1-60, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | TRA-1-60, Human |
| Clone | REA157 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | Vio 488 conjugate |
| Size | 100 µL |
| Concentration | n/a |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | TRA-1-60 Antibody, anti-human, Vio® 488, REAfinity™. Clone REA157 recognizes the TRA-1-60 antigen, a neuraminidase-resistant carbohydrate epitope expressed on podocalyxin, which is a transmembrane glycoprotein. Podocalyxin is a member of the CD34-related family of sialomucins and is recognized as a stem cell and tumor marker. TRA-1-60 antigen is expressed on the surface of human embryonic stem cells (ESC), embryonic germ cells (EG), and embryonic carcinoma cells (EC). Expression of TRA-1-60 is lost upon differentiation and thus it can be used to assess the differentiation stage of the cells. TRA-1-60 can be detected in the serum of patients with germ cell tumors which contain an EC component. | Additional information: Clone REA157 displays negligible binding to Fc receptors. | |
| Immunogen | n/a |
| Other Names | PODXL, Gp200, PC, PCLP, PCLP-1, Podocalyxin |
| Gene, Accession # | Gene ID: 5420 |
| Catalog # | 130-106-872 |
| Price | $345 |
| Order / More Info | TRA-1-60, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Andrews, P. W. et al. (1984) Three monoclonal antibodies defining distinct differentiation antigens associated with different high molecular weight polypeptides on the surface of human embryonal carcinoma cells. Hybridoma 3 (4): 347-361. | Lajer, H. et al. (2002) Clinical use of serum TRA-1-60 as tumor marker in patients with germ cell cancer. Int. J. Cancer 100 (2): 244-246. | Schopperle, W. M. et al. (2007) The TRA-1-60 and TRA-1-81 human pluripotent stem cell markers are expressed on podocalyxin in embryonal carcinoma. Stem Cells 25 (3): 723-730. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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