CD301 (CLEC10A), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD301 (CLEC10A), Mouse |
| Clone | REA687 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | PE-Vio 770 conjugate |
| Size | 30 µg in 1 mL |
| Concentration | 1:10 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD301 (CLEC10A) Antibody, anti-mouse, PE-Vio® 770, REAfinity™. Clone REA687 recognizes the mouse CD301 (CLEC10A) antigen, which is a 40 kDa type II transmembrane glycoprotein expressed by immature DCs and activated macrophages. Mouse CD301 has two homologue genes, CD301a (MGL1) and CD301b (MGL2). CD301 is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily which plays a role in cell adhesion, cell-cell signaling, glycoprotein turnover, inflammation, and immune response. CD301 binds in a calcium-dependent manner to terminal galactose and N-acetylgalactosamine units, linked to serine or threonine. | Additional information: Clone REA687 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | Clec10a, MGL, M-ASGP-BP-1 |
| Gene, Accession # | Gene ID: 17312 |
| Catalog # | 130-110-289 |
| Price | $156 |
| Order / More Info | CD301 (CLEC10A), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Denda-Nagai, K. et al. (2010) Distribution and function of macrophage galactose-type C-type lectin 2 (MGL2/CD301b): efficient uptake and presentation of glycosylated antigens by dendritic cells. J. Biol. Chem. 285 (25): 19193-19204. | Tsuiji, M. et al. (2002) Molecular cloning and characterization of a novel mouse macrophage C-type lectin, mMGL2, which has a distinct carbohydrate specificity from mMGL1. J. Biol. Chem. 277 (32): 28892-28901. | Singh, S. K. et al. (2009) Characterization of murine MGL1 and MGL2 C-type lectins: distinct glycan specificities and tumor binding properties. Mol. Immunol. 46 (6): 1240-1249. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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