CD150 (SLAM), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityCD150 (SLAM), Human
CloneREA151
Host SpeciesRecombinant Human
Reactive Specieshuman
IsotypeIgG1
Formatbiotin conjugate
Size30 tests in 300 µL
Concentration1:11
ApplicationsFlow cytometry
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DescriptionCD150 (SLAM) Antibody, anti-human, Biotin, REAfinity™. Clone REA151 recognizes CD150, a 70 kDa cell surface glycoprotein also known as SLAM, and belongs to the Ig superfamily. It acts as a self ligand. Expression of CD150 is found on B cells, dendritic cells, and activated/memory T cells and it is involved in functions such as stimulation, proliferation, and inhibition of apoptosis of B cells, stimulation and IFN-γ production in T?1 T cell clones. CD150 has been identified as the second receptor for measles virus. | Additional information: Clone REA151 displays negligible binding to Fc receptors. | |
Immunogenn/a
Other NamesSLAMF1, CDw150, SLAM, IPO3
Gene, Accession #Gene ID: 6504
Catalog #130-099-675
Price$99
Order / More InfoCD150 (SLAM), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesHowie, D. et al. (2002) Molecular dissection of the signaling and costimulatory functions of CD150 (SLAM): CD150/SAP binding and CD150-mediated costimulation. Blood 99: 957-965. | Wang, N. et al. (2001) CD150 is a member of a family of genes that encode glycoproteins on the surface of hematopoietic cells. Immunogenetics 53 (5): 382-394. | Welstead, G. G. et al. (2004) Mechanism of CD150 (SLAM) down regulation from the host cell surface by measles virus hemagglutinin protein. J. Virol. 78: 9666 -9674.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

macs@miltenyibiotec.de

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