EphA2, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | EphA2, Mouse |
| Clone | REA579 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | biotin conjugate |
| Size | 30 µg in 1 mL |
| Concentration | 1:10 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | EphA2 Antibody, anti-mouse, Biotin, REAfinity™. Clone REA579 recognizes the mouse EphA2 antigen, which is a member of the receptor tyrosine kinases that are activated in response to binding ephrin. The ephrin receptor (Eph) family of receptor tyrosine kinases is the largest family of receptor tyrosine kinases. | Ephs are divided into two subclasses, EphAs and EphBs, based on sequence similarity and on their binding affinity to ephrin-A ligands or the transmembrane-bound ephrin-B ligands. | Eph receptors and ephrins regulate the adhesion of endothelial cells and are required for the remodeling of blood vessels and may be involved in cell-cell interactions guiding early hindbrain development. It is up-regulated on many aggressive carcinoma cells including aggressive ovarian, cervical and breast carcinomas, and lung cancer. | Additional information: Clone REA579 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | Eck, Myk2, Sek2 |
| Gene, Accession # | Gene ID: 13836 |
| Catalog # | 130-109-138 |
| Price | $57 |
| Order / More Info | EphA2, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | No authors listed (1997) Unified nomenclature for Eph family receptors and their ligands, the ephrins. Eph Nomenclature Committee. Cell 90 (3): 403-404. | Gilardi-Hebenstreit, P. et al. (1992) An Eph-related receptor protein tyrosine kinase gene segmentally expressed in the developing mouse hindbrain. Oncogene 7 (12): 2499-2506. | Ruiz, J. C. and Robertson, E. J. (1994) The expression of the receptor-protein tyrosine kinase gene, eck, is highly restricted during early mouse development. Mech. Dev. 46 (2): 87-100. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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