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Antigenic Specificity | Ly-6C, Mouse |
Clone | REA796 |
Host Species | Recombinant Human |
Reactive Species | mouse |
Isotype | IgG1 |
Format | PE-Vio 770 conjugate |
Size | 150 µg in 1 mL |
Concentration | 1:50 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Ly-6C Antibody, anti-mouse, PE-Vio® 770, REAfinity™. Clone REA796 recognizes the mouse Ly-6C antigen, which is a 14-17 kDa GPI-linked cell surface antigen that belongs to the Ly-6 family of murine surface glycoproteins. It is expressed on monocytes in the bone marrow and shortly after their migration into the circulation. Moreover, Ly-6C is expressed on memory T cells and CD11lowCD45R(B220)+ mPDCA1+ plasmacytoid dendritic cells (pDCs) in different organs. | Additional information: Clone REA796 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | Ly-6C1, Ly-6C.2, Ly-6C2 |
Gene, Accession # | Gene ID: 100041546 |
Catalog # | 130-111-780 |
Price | $450 |
Order / More Info | Ly-6C, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Shevach, E. M. and Korty, P. E. (1989) Ly-6: a multigene family in search of a function. Immunol. Today 10: 195-220. | Schlueter, A. J. et al. (1997) Distribution of Ly-6C on lymphocyte subsets: I. Influence of allotype on T lymphocyte expression. J Immunol 158: 4211-4222. | Hanninen, A. et al. (1997) Ly-6C regulates endothelial adhesion and homing of CD8+ T cells by activating integrin-dependent adhesion pathways. Proc. Natl. Acad. Sci. U.S.A. 94: 6898-6903. | Curtsinger, J. M. et al. (1998) CD8+ memory T cells (CD44high, Ly-6C+) are more sensitive than naive cells to (CD44low, Ly-6C-) to TCR/CD8 signaling in response to antigen. J Immunol 160: 3236-3243. | Sunderkotter, C. et al. (2004) Subpopulations of mouse blood monocytes differ in maturation stage and inflammatory response. J Immunol 172: 4410-4417. |