TCR Vβ4, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | TCR Vβ4, Mouse |
| Clone | REA729 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | PerCP-Vio 700 conjugate |
| Size | 150 µg in 1 mL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | TCR Vβ4 Antibody, anti-mouse, PerCP-Vio® 700, REAfinity™. Clone REA729 recognizes the mouse V beta 4 T cell receptor (TCR Vβ4). The T cell receptor (TCR) is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable α and β chains expressed as part of a complex with the invariant CD3 chain molecules. T cells expressing this receptor are referred to as TCRα/β T cells, though a minority of T cells express an alternate receptor, formed by variable γ and δ chains, referred as TCRγ/δ T cells. TCR Vβ4 is a variant of the TCR β chain and is expressed on mouse strains with the a (e.g., Balb/c), b (e.g., C57BL/6) and c (e.g., SJL, NOD) haplotypes in the Tcrb gene complex. | Additional information: Clone REA729 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | TCR Vb4 |
| Gene, Accession # | Gene ID: 100124660 |
| Catalog # | 130-110-986 |
| Price | $450 |
| Order / More Info | TCR Vβ4, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Singer, P. A. et al. (1988) T-cell receptor alpha-chain variable-region haplotypes of normal and autoimmune laboratory mouse strains. Proc. Natl. Acad. Sci. U.S.A. 85 (20): 7729-7733. | Tomonari, K. et al. (1990) Correlation between the V beta 4+ CD8+ T-cell population and the H-2d haplotype. Immunogenetics 31 (5-6): 333-339. | Sugihara, S. et al. (1993) Autoimmune thyroiditis induced in mice depleted of particular T cell subsets. Characterization of thyroiditis-inducing T cell lines and clones derived from thyroid lesions. J Immunol 150 (2): 683-694. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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