CD154, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD154, Mouse |
| Clone | REA785 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | biotin conjugate |
| Size | 30 µg in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD154 Antibody, anti-mouse, Biotin, REAfinity™. Clone REA785 specifically recognizes the mouse CD154 antigen, a 39 kDa transmembrane glycoprotein also known as CD40L, gp39, T-BAM, TRAP, or Ly-62. CD154 is transiently up-regulated on activated CD4+ T cells and plays an important role as a costimulatory molecule in T cell/antigen-presenting cell interactions through ligation of CD40. Due to its transient expression within hours after activation, CD154 can be used as a marker for activated antigen-specific CD4+ T cells. Adding a CD40-blocking antibody during the stimulation of cell suspensions prevents the down-regulation of CD154. Blocking of CD40 is not required for intracellular detection of CD154 expression or if a pure population of enriched T cells is used. | Additional information: Clone REA785 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | CD40LG, CD40L, HIGM1, IGM, IMD3, Ly-62, T-BAM, TRAP, TNFSF5, gp39 |
| Gene, Accession # | Gene ID: 21947 |
| Catalog # | 130-111-359 |
| Price | $66 |
| Order / More Info | CD154, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Armitage, R. J. et al. (1992) Molecular and biological characterization of a murine ligand for CD40. Nature 357 (6373): 80-82. | Tsitsikov, E. N. et al. (1994) Structure of the murine CD40 ligand gene. Mol. Immunol. 31 (12): 895-900. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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