MYH7B, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | MYH7B, Human |
| Clone | REAL1165 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | n/a |
| Format | phycoerythrin (PE) conjugate |
| Size | 200 µL |
| Concentration | n/a |
| Applications | MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | MYH7B Antibody, anti-human, PE, REAdye_lease™. Clone REAL1165 is an antibody fragment derived from the full MYH7B antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL1165 recognizes human protein MYH7B, also known as myosin, heavy chain 7B or Myosin-7B, which is a member of the motor-domain superfamily. MYH7B is expressed in extraocular muscles and muscle spindles in heart, skeletal muscle and testis, but also in liver, spleen, lung and pancreas. MYH7B plays a role in muscle contraction. MYH7B is supposed to cause heart diseases including Hypertrophic cardiomyopathy (HCM), Left Ventricular Noncompaction (LVHT) and Dilated Cardiomyopathy. | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675). |
| Immunogen | n/a |
| Other Names | Myosin-7B, Antigen MLAA-21, Myosin cardiac muscle beta chain, KIAA1512, Slow A MYH14 |
| Gene, Accession # | n/a |
| Catalog # | 130-128-921 |
| Price | $470 |
| Order / More Info | MYH7B, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Peter, A. K. et al. (2019) Expression of Normally Repressed Myosin Heavy Chain 7b in the Mammalian Heart Induces Dilated Cardiomyopathy. J Am Heart Assoc. 8 (15): . | Rossi, A. C. et al. (2010) Two novel/ancient myosins in mammalian skeletal muscles: MYH14/7b and MYH15 are expressed in extraocular muscles and muscle spindles. J Physiol 588: 353-364. | Desjardins, P. R. et al. (2002) Evolutionary implications of three novel members of the human sarcomeric myosin heavy chain gene family. Mol. Biol. Evol. 19 (4): 375-393. | Chen, P. et al. (2020) MYH7B variants cause hypertrophic cardiomyopathy by activating the CaMK-signaling pathway. Sci. China Life Sci. 63 (9): 1347-1362. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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