E4BP4 (NFIL3), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | E4BP4 (NFIL3), Human |
| Clone | REA732 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | allophycocyanin (APC) conjugate |
| Size | 30 tests in 60 µL |
| Concentration | 1:50 |
| Applications | Intracellular flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | E4BP4 (NFIL3) Antibody, anti-human, APC, REAfinity™. Clone REA732 recognizes the human E4BP4 (NFIL3) antigen, a basic leucine zipper transcription factor that is regulated by the cytokine IL-3. E4BP4 is highly expressed in lung and in lower levels in brain and spinal cord. E4BP4 acts with members of the PAR family of transcription factors with which it shares DNA-binding specificity. It plays a role in commitment to cell survival versus apoptosis, anti-inflammatory response, and transcriptional controlling of the mammalian circadian clock. Furthermore, E4BP4 plays an essential role in the development of CD8α+ conventional dendritic cells (cDCs). | Additional information: Clone REA732 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | NFIL3 |
| Gene, Accession # | Gene ID: 4783 |
| Catalog # | 130-111-435 |
| Price | $142 |
| Order / More Info | E4BP4 (NFIL3), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Kashiwada, M. et al. (2011) NFIL3/E4BP4 is a key transcription factor for CD8α? dendritic cell development. Blood 117 (23): 6193-6197. | Cowell, I. G. (2002) E4BP4/NFIL3, a PAR-related bZIP factor with many roles. Bioessays 24 (11): 1023-1029. | Hulme, D. J. et al. (2000) Exclusion of NFIL3 as the gene causing hereditary sensory neuropathy type I by mutation analysis. Hum. Genet. 106 (6): 594-596. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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