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Antigenic Specificity | Amyloid A, Human |
Clone | REA931 |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | IgG1 |
Format | allophycocyanin (APC) conjugate |
Size | 200 µL |
Concentration | 1:50 |
Applications | Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Amyloid A Antibody, anti-human, APC, REAfinity™. Clone REA931 recognizes the human protein Amyloid A type AA, located in plasma. Amyloid A, an acute phase marker, is an apolipoprotein of the HDL (high-density lipoprotein) complex, which is highly expressed in response to inflammation and tissue injury. Amyloid A increases the export of free cholesterol/phospholipid for reuse in the membranes of several cells, which are neccessary during acute inflammation and repair. REA931 recognizes amyloid deposits in all organs and tissues, also kidney and rectum. | Additional Information: Clone REA931 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | Amyloid fibril protein AA, OC, PIG 4, PIG4, SAA 1, SAA |
Gene, Accession # | Gene ID: 6288 |
Catalog # | 130-115-483 |
Price | $325 |
Order / More Info | Amyloid A, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Donini, U. et al. (1989) Immunoelectron microscopic classification of amyloid in renal biopsies. J. Histochem. Cytochem. 37 (7): 1101-1106. | Uhlar, C. M. et al. (1999) Serum amyloid A, the major vertebrate acute-phase reactant. Eur. J. Biochem. 265 (2): 501-523. | Manley, P. N. et al. (2006) Rapid recycling of cholesterol: the joint biologic role of C-reactive protein and serum amyloid A. Med. Hypotheses 66 (4): 784-792. |