CD134 (OX40), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityCD134 (OX40), Mouse
CloneREA625
Host SpeciesRecombinant Human
Reactive Speciesmouse
IsotypeIgG1
Formatbiotin conjugate
Size30 µg in 1 mL
Concentration1:10
ApplicationsFlow cytometry
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DescriptionCD134 (OX40) Antibody, anti-mouse, Biotin, REAfinity™. Clone REA625 recognizes the CD134 antigen, also known as OX40 receptor, a 50 kDa type I membrane glycoprotein of the tumor necrosis factor/nerve growth factor receptor (TNFR/NGFR) family. OX40 is a secondary costimulatory molecule, which is expressed after 24 to 72 hours following activation. It is expressed on activated mouse T cells and B cells. The OX40 receptor binds to the OX40 ligand (CD252) to provide a costimulatory signal which is independent of CD28. | Additional information: Clone REA625 displays negligible binding to Fc receptors. |
Immunogenn/a
Other NamesOX40L receptor, OX-40, TNFRSF4
Gene, Accession #Gene ID: 22163
Catalog #130-111-582
Price$57
Order / More InfoCD134 (OX40), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesAkiba, H. et al. (1999) CD28-independent costimulation of T cells by OX40 ligand and CD70 on activated B cells. J Immunol 162 (12): 7058-7066. | Kjaergaard, J. et al. (2001) Augmentation versus inhibition: effects of conjunctional OX-40 receptor monoclonal antibody and IL-2 treatment on adoptive immunotherapy of advanced tumor. J Immunol 167: 6669-6677. | al-Shamkhani, A. et al. (1996) OX40 is differentially expressed on activated rat and mouse T cells and is the sole receptor for the OX40 ligand. Eur. J. Immunol. 26 (8): 1695-1699. | Hong, G. U. et al. (2015) IgE and IgA produced by OX40-OX40L or CD40-CD40L interaction in B cells-mast cells re-activate FcεRI or FcαRI on mast cells in mouse allergic asthma. Eur. J. Pharmacol. 754: 199-210.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

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