CD28, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityCD28, Mouse
Clone37.51
Host SpeciesHamster
Reactive Speciesmouse
IsotypeIgG2λ
Formatbiotin conjugate
Size100 µg in 1 mL
Concentrationn/a
ApplicationsFunctional assay
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DescriptionCD28 Antibody, anti-mouse, Biotin-functional grade. The CD28 antibody is specific for the mouse CD28 costimulatory molecule, expressed on most thymocytes, CD4+ and CD8+ T cells, and NK cells. Expression is down-regulated at late stages of terminal effector T cell differentiation. CD28 is a homodimeric type I transmembrane protein of the Ig receptor superfamily, composed of disulfide-linked 45 kDa subunits. Ligation of CD28 with CD80 (B7-1) and CD86 (B7-2) provides a costimulatory signal for T cell activation.
Immunogenn/a
Other NamesT44, Tp44
Gene, Accession #Gene ID: 12487
Catalog #130-093-183
Price$127
Order / More InfoCD28, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesGross, J. A. et al. (1992) Identification and distribution of the costimulatory receptor CD28 in the mouse. J Immunol 149 (2): 380-388. | Harding, F. A. et al. (1992) CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones. Nature 356 (6370): 607-609.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

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