Edit |   |
---|---|
Antigenic Specificity | CD86, Human |
Clone | FM95 |
Host Species | Mouse |
Reactive Species | human, nonhuman primate |
Isotype | IgG1κ |
Format | PerCP-Vio 700 conjugate |
Size | 100 tests in 200 µL |
Concentration | 1:50 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD86 Antibody, anti-human, PerCP-Vio® 700. CD86, also known as B7-2 or B70, is an 80 kDa molecule and a member of the immunoglobulin superfamily. Together with CD80 (B7-1) it belongs to the B7 family of costimulatory molecules. CD86 is expressed on activated B and T cells, dendritic cells (DCs), and monocytes/macrophages. The interaction of CD86 with its ligands CD28 and CD152 (CTLA- 4) plays a critical role in induction and regulation of immune responses, e.g., cross-talk between T and B cells, T cell costimulation, or immunoglobulin class-switching. Binding of CD86 to CD28 on T cells results in transduction of costimulatory signals for activation or proliferation of T cells, or cytokine production. |
Immunogen | n/a |
Other Names | B7-2, B70, CD28LG2, LAB72 |
Gene, Accession # | Gene ID: 942 |
Catalog # | 130-113-574 |
Price | $365 |
Order / More Info | CD86, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | n/a |