LRP-4, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityLRP-4, Human
CloneREA552
Host SpeciesRecombinant Human
Reactive Specieshuman
IsotypeIgG1
Formatphycoerythrin (PE) conjugate
Size30 tests in 60 µL
Concentration1:50
ApplicationsFlow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
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DescriptionLRP-4 Antibody, anti-human, PE, REAfinity™. Clone REA552 recognizes the human LRP-4 antigen, a β-propeller containing protein, which is a member of the low density lipoprotein-receptor gene family and a modulator of extracellular cell signaling pathways in development. LRP-4 is expressed in bone and cultured osteoblasts and binds Dkk1 and sclerostin in vitro. It plays a physiological role in the regulation of bone growth and turnover. | Additional information: Clone REA552 displays negligible binding to Fc receptors.
Immunogenn/a
Other NamesLrp4, CLSS, CMS17, LRP10, MEGF7, SOST2, KIAA0816
Gene, Accession #Gene ID: 4038
Catalog #130-126-563
Price$146
Order / More InfoLRP-4, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesHoldsworth, G. et al. (2012) Characterization of the interaction of sclerostin with the low density lipoprotein receptor-related protein (LRP) family of Wnt co-receptors. J. Biol. Chem. 287 (32): 26464-26477. | Leupin, O. et al. (2011) Bone overgrowth-associated mutations in the LRP4 gene impair sclerostin facilitator function. J. Biol. Chem. 286 (22): 19489-19500. | Choi, H. Y. et al. (2009) Lrp4, a novel receptor for Dickkopf 1 and sclerostin, is expressed by osteoblasts and regulates bone growth and turnover in vivo. PLoS One 4 (11): e7930.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

macs@miltenyibiotec.de

https://www.miltenyibiotec.com

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