HLA-A9, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityHLA-A9, Human
CloneREA127
Host SpeciesRecombinant Human
Reactive Specieshuman
IsotypeIgG1
Formatbiotin conjugate
Size100 tests in 1 mL
Concentration1:11
ApplicationsMass cytometry
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DescriptionHLA-A9 Antibody, anti-human, Biotin, REAfinity™. Clone REA127 recognizes HLA A9, a class I human leukocyte antigen (HLA). Expressed on the surface of most nucleated cells, class I molecules are heterodimeric molecules and consist of a type I integral membrane α heavy chain and soluble β2 microglobulin protein. The extracellular region of the heavy chain further consists of 3 domains, of which one comprises the peptide binding groove. Antigens binding to class I molecules are 8-10 amino acids long and play an important role in recognition of the virus infected and malignant cells by cytotoxic T lymphocytes (CTLs). In addition, class I molecules interact with NK cell receptors to modulate the activity of NK cells. | Additional information: Clone REA127 displays negligible binding to Fc receptors.
Immunogenn/a
Other NamesHLA-A
Gene, Accession #Gene ID: 3105
Catalog #130-099-533
Price$264
Order / More InfoHLA-A9, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesHewitt, E. W. et al. (2003) The MHC class I antigen presentation pathway: strategies for viral immune evasion. Immunology 110 (2): 163-169.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

macs@miltenyibiotec.de

https://www.miltenyibiotec.com

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