GFAP, Human/Mouse/Rat Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | GFAP, Human/Mouse/Rat |
| Clone | REA335 |
| Host Species | Recombinant Human |
| Reactive Species | human, mouse, rat |
| Isotype | IgG1 |
| Format | phycoerythrin (PE) conjugate |
| Size | 100 tests in 200 µL |
| Concentration | 1:50 |
| Applications | Intracellular flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | GFAP Antibody, anti-human/mouse/rat, PE, REAfinity™. Clone REA335 recognizes the human, mouse, and rat glial fibrillary acidic protein (GFAP), the main intermediate filament protein in mature astrocytes and an important component of the cytoskeleton in astrocytes during development. GFAP is expressed exclusively in astrocytes in the central nervous system. It has been shown to be involved in astrocyte functions, which are important during regeneration, synaptic plasticity, and reactive gliosis. Moreover, different subpopulations of astrocytes have been identified, which are likely to have distinctive tasks in brain physiology and pathology, and which are not only classified by their spatial and temporal appearance, but also by their specific expression of intermediate filaments, including distinct GFAP isoforms. | Additional information: Clone REA335 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | ALXDRD |
| Gene, Accession # | Gene ID: 2670 |
| Catalog # | 130-118-351 |
| Price | $315 |
| Order / More Info | GFAP, Human/Mouse/Rat Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Reeves, S. A. et al. (1989) Molecular cloning and primary structure of human glial fibrillary acidic protein. Proc. Natl. Acad. Sci. U.S.A. 86 (13): 5178-5182. | Baba, H. et al. (1997) GFAP gene expression during development of astrocyte. Dev. Neurosci. 19 (1): 49-57. | Middeldorp, J. et al. (2011) GFAP in health and disease. Prog. Neurobiol. 93 (3): 421-443. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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