Ly-6G, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityLy-6G, Mouse
CloneREAL176
Host SpeciesRecombinant Human
Reactive Speciesmouse
Isotypen/a
Formatphycoerythrin (PE) conjugate
Size30 µg in 200 µL
Concentration1:50
ApplicationsFlow cytometry
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DescriptionLy-6G Antibody, anti-mouse, PE, REAlease®. Clone REAL176 is an antibody fragment derived from the full Ly-6G antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAlease Complex to bind markers with high avidity. | Clone REAL176 recognizes the mouse Ly-6G (Lymphocyte antigen 6G) antigen, a 21-25-kDa glycosylphosphatidylinositol (GPI) linked protein which is highly expressed on neutrophilic granulocytes. Expression greatly increases during granulocyte maturation. To a lower extent, Ly-6G is also expressed during the development of monocytes. In mouse bone marrow samples, Ly-6G is primarily detected on granulocytes, but not on lymphocytes or erythrocytes. Ligation of Ly-6G in animals with an underlying background inflammation (induced by TNF-α) leads to profound cardiovascular and respiratory responses, including severe breathing difficulties, leukocyte and platelet aggregation, and coagulation, leading to microvessel obstruction and subsequent death. | The REAlease Kits consist of the respective fluorochrome-conjugated REAlease Complexes and the REAlease Support Kit for removal of the REAlease Complexes and optional relabeling with different fluorochrome-conjugated REAlease Complexes.
Immunogenn/a
Other NamesLy-6G.1, Ly6g
Gene, Accession #n/a
Catalog #130-119-914
Price$70
Order / More InfoLy-6G, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific Referencesn/a
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

macs@miltenyibiotec.de

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