CD134 (OX40), Rat Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD134 (OX40), Rat |
| Clone | REA540 |
| Host Species | Recombinant Human |
| Reactive Species | rat |
| Isotype | IgG1 |
| Format | biotin conjugate |
| Size | 30 µg in 1 mL |
| Concentration | 1:10 |
| Applications | Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD134 (OX40) Antibody, anti-rat, Biotin, REAfinity™. Clone REA540 recognizes the rat CD134 (OX40) antigen, a 50 kDa glycoprotein which is a member of the TNFR superfamily. It contains a typical signal sequence and a single putative transmembrane sequence of 25 predominantly hydrophobic amino acids giving an extracellular domain of 191 amino acids and a cytoplasmic domain of 36 amino acids. The expression of CD134 is restricted to activated rat CD4+ T cells and is up-regulated within hours after activation. CD134 and its ligand CD252 (CD134L, OX40L), which is expressed on activated T and B lymphocytes and also a member of the tumor necrosis factor receptor superfamily, were suggested to mediate the interaction between T cells and B cells. | Additional information: Clone REA540 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | TNFRSF4, OX-40, Txgp1, MRC OX40 |
| Gene, Accession # | Gene ID: 25572 |
| Catalog # | 130-108-185 |
| Price | $57 |
| Order / More Info | CD134 (OX40), Rat Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Calderhead, D. M. et al. (1993) Cloning of mouse Ox40: a T cell activation marker that may mediate T-B cell interactions. J Immunol 151: 5261-5271. | Mallett, S. et al. (1990) Characterization of the MRC OX40 antigen of activated CD4 positive T lymphocytes--a molecule related to nerve growth factor receptor. EMBO J. 9 (4): 1063-1068. | Al-Shamkhanie, A. et al. (1997) Affinity and kinetics of the interaction between soluble trimeric OX40 ligand, a member of the tumor necrosis factor superfamily, and its receptor OX40 on activated T cells. J. Biol. Chem. 272: 5275-5282. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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