TLT-2, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | TLT-2, Human |
| Clone | REA514 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | phycoerythrin (PE) conjugate |
| Size | 100 tests in 1 mL |
| Concentration | 1:11 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | TLT-2 Antibody, anti-human, PE, REAfinity™. Clone REA514 recognizes the human Trem-like transcript 2 (TLT-2) antigen, a single-pass type I membrane protein, which is also known as triggering receptor expressed on myeloid cells-like protein 2 (TREML2). TLT-2 is one of the conserved TREM family members, which is expressed on B cells, T cells, macrophages, and neutrophils. It is suggested to play an important role in the immune system, for it is not only highly expressed in inflammation, but also promotes the proliferation of T cells and the production of cytokines. | Additional information: Clone REA514 displays negligible binding to Fc receptors |
| Immunogen | n/a |
| Other Names | TREML2, C6orf76, TLT2 |
| Gene, Accession # | Gene ID: 79865 |
| Catalog # | 130-107-786 |
| Price | $310 |
| Order / More Info | TLT-2, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Halpert, M. M. et al. (2011) TLT2 potentiates neutrophil antibacterial activity and chemotaxis in response to G protein-coupled receptor-mediated signaling. J Immunol 187 (5): 2346-2355. | Hashiguchi, M. et al. (2008) Triggering receptor expressed on myeloid cell-like transcript 2 (TLT-2) is a counter-receptor for B7-H3 and enhances T cell responses. Proc. Natl. Acad. Sci. U.S.A. 105 (30): 10495-10500. | Allcock, R. J. et al. (2003) The human TREM gene cluster at 6p21.1 encodes both activating and inhibitory single IgV domain receptors and includes NKp44. Eur. J. Immunol. 33 (2): 567-577. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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