Cytokeratin, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | Cytokeratin, Human |
| Clone | CK3-6H5 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1κ |
| Format | fluorescein (FITC) conjugate |
| Size | 30 tests in 60 µL |
| Concentration | 1:50 |
| Applications | Intracellular flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Cytokeratin Antibody, anti-human, FITC. Cytokeratins are typical intermediate filaments of the cytoskeleton of epithelial cells. They are a biochemically highly diverse multigene family of polypeptides with molecular masses ranging from 40 to 68 kDa. Until now 20 distinct cytokeratin polypeptides have been described, which can be divided into an acidic (type I) and a neutral-basic (type II) subfamily. The cytokeratin expression profile within one cell characterizes the type of epithelia and also the degree of maturation or differentiation. Most malignant cells which have their origin in epithelial tissue express a certain cytokeratin profile, which can be used for classifying carcinomas and for distinguishing carcinomas from malignant tumors of nonepithelial origin. The Anti-Cytokeratin (CK3-6H5) antibody is a pan-cytokeratin-specific antibody targeting cytokeratins from simple epithelia. It crossblocks Cam5.2, an antibody specific for cytokeratin 7 and 8, and has been shown to react with native cytokeratin preparations containing cytokeratins 8, 18, and 19 as well as with recombinant cytokeratin 8. |
| Immunogen | n/a |
| Other Names | KRT7, KRT8, KRT18, KRT19 |
| Gene, Accession # | Gene ID: 3855, 3856, 3875, 3880 |
| Catalog # | 130-119-141 |
| Price | $94 |
| Order / More Info | Cytokeratin, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Makin, C. A. et al. (1984) Monoclonal antibody to cytokeratin for use in routine histopathology. J Clin Pathol 37: 975-983. | Balasubramanian, P. et al. (2012) Multiparameter analysis, including EMT markers, on negatively enriched blood samples from patients with squamous cell carcinoma of the head and neck. PLoS One 7 (7): . | Xin, H. et al. (2014) Establishment and characterization of 7 novel hepatocellular carcinoma cell lines from patient-derived tumor xenografts. PLoS One 9 (1): e85308. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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