CD218 (IL-18Rα), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityCD218 (IL-18Rα), Human
CloneH44
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1κ
Formatbiotin conjugate
Size30 tests in 300 µL
Concentration1:11
ApplicationsFlow cytometry
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DescriptionCD218 (IL-18Rα) Antibody, anti-human, Biotin. Clone H44 recognizes the CD218 antigen, which is also known as interleukin-18 receptor α chain (IL-18Rα) receptor, is an heterodimeric receptor complex and composed of the IL-18Rα chain and the IL-1 receptor accessory protein-like (IL-1RacPL) or IL-18Rβ chain. CD218 represents the ligand-binding chain, whereas IL-18Rβ is suggested to assist in the formation of a high affinity complex and mediates intracellular signals. IL-18R is expressed on a variety of cells including macrophages, neutrophils, natural killer (NK) cells, endothelial, and smooth muscle cells and an upregulated expression is observed on naive T cells, T helper cell type 1 (T?1) cells, and B cells, in the presence of IL-12.
Immunogenn/a
Other NamesIL18R1, CD218a, CDw218a, IL-1Rrp, IL18RA, IL1RRP
Gene, Accession #n/a
Catalog #130-101-673
Price$93
Order / More InfoCD218 (IL-18Rα), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesKim, S. H. et al. (2001) Functional reconstitution and regulation of IL-18 activity by the IL-18Rβ chain. J Immunol 166: 148-154. | Nakamura, S. et al. (2000) Expression and responsiveness of human interleukin-18 receptor (IL-18R) on hematopoietic cell lines. Leukemia 14 (6): 1052-1059.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

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