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Antigenic Specificity | Ly-6G, Mouse |
Clone | REAL176 |
Host Species | Recombinant Human |
Reactive Species | mouse |
Isotype | n/a |
Format | fluorescein (FITC) conjugate |
Size | 200 µL |
Concentration | n/a |
Applications | Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunohistochemistry, Immunofluorescence |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Ly-6G Antibody, anti-mouse, FITC, REAlease®. Clone REAL176 is an antibody fragment derived from the full Ly-6G antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAlease Complex to bind markers with high avidity. | Clone REAL176 recognizes the mouse Ly-6G (Lymphocyte antigen 6G) antigen, a 21-25-kDa glycosylphosphatidylinositol (GPI) linked protein which is highly expressed on neutrophilic granulocytes. Expression greatly increases during granulocyte maturation. To a lower extent, Ly-6G is also expressed during the development of monocytes. In mouse bone marrow samples, Ly-6G is primarily detected on granulocytes, but not on lymphocytes or erythrocytes. Ligation of Ly-6G in animals with an underlying background inflammation (induced by TNF-α) leads to profound cardiovascular and respiratory responses, including severe breathing difficulties, leukocyte and platelet aggregation, and coagulation, leading to microvessel obstruction and subsequent death. | The REAlease Kits consist of the respective fluorochrome-conjugated REAlease Complexes and the REAlease Support Kit for removal of the REAlease Complexes and optional relabeling with different fluorochrome-conjugated REAlease Complexes. |
Immunogen | n/a |
Other Names | Ly-6G.1, Ly6g |
Gene, Accession # | n/a |
Catalog # | 130-119-910 |
Price | $51 |
Order / More Info | Ly-6G, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | n/a |