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Antigenic Specificity | CD31, Mouse |
Clone | 390 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2aκ |
Format | allophycocyanin (APC) conjugate |
Size | 30 µg in 200 µL |
Concentration | 1:50 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD31 Antibody, anti-mouse, APC. Clone 390 reacts with the cell surface protein CD31. The murine CD31 antigen is also known as PECAM-1. The encoded protein is a single-pass type I membrane protein containing six Ig-like C2-type (immunoglobulin-like) domains and functions as cell adhesion molecule. CD31 is present on mature endothelial cells as well as on most leukocyte subtypes and platelets where the expression level can vary. Besides its function in exhibiting adhesive properties, the protein is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions. |
Immunogen | n/a |
Other Names | PECAM1, Pecam, EndoCAM, GPIIa |
Gene, Accession # | Gene ID: 18613 |
Catalog # | 130-123-813 |
Price | $93 |
Order / More Info | CD31, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Xie, Y. and Muller, W. A. (1993) Molecular cloning and adhesive properties of murine platelet/endothelial cell adhesion molecule 1. Proc. Natl. Acad. Sci. U.S.A. 90 (12): 5569-5573. | Woodfin, A. et al. (2007) PECAM-1: a multi-functional molecule in inflammation and vascular biology. Arterioscler. Thromb. Vasc. Biol. 27 (12): 2514-2523. | van Buul, J. D. and Hordijk, P. L. (2008) Endothelial signaling by Ig-like cell adhesion molecules. Transfus. Clin. Biol. 15 (1-2): 3-6. |