CD197 (CCR7), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD197 (CCR7), Mouse |
| Clone | REA685 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | allophycocyanin (APC) conjugate |
| Size | 30 µg in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD197 (CCR7) Antibody, anti-mouse, APC, REAfinity™. Clone REA685 recognizes the mouse CD197 (CCR7) antigen, a chemokine receptor for chemokines CCL19 and CCL21. CD197, like other chemokine receptors has seven transmembrane spanning domains and signals via G proteins. Expression of CD197 is found on semi-mature and mature dendritic cells (DCs), naive B and T cells, regulatory T (Treg) cells, a subpopulation of T cells called central memory T cells, and non-immune malignant cells. CD197 is involved in regulating homing of immune cells, immunity to pathogens, immune tolerance, development and function of Tregs, and manifestation of autoimmunity. | Additional information: Clone REA685 displays negligible binding to Fc receptors. | |
| Immunogen | n/a |
| Other Names | C-C chemokine receptor type 7, C-C CKR-7, CC-CKR-7, CCR-7, EBI1, MIP-3 beta receptor, EBI-1 |
| Gene, Accession # | Gene ID: 12775 |
| Catalog # | 130-126-307 |
| Price | $92 |
| Order / More Info | CD197 (CCR7), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Ritter, U. et al. (2004) Analysis of the CCR7 expression on murine bone marrow-derived and spleen dendritic cells. J. Leukoc. Biol. 76 (2): 472-476. | Bjorkdahl, O. et al. (2003) Characterization of CC-chemokine receptor 7 expression on murine T cells in lymphoid tissues. Immunology 110 (2): 170-179. | Forster, R. et al. (2008) CCR7 and its ligands: balancing immunity and tolerance. Nat. Rev. Immunol. 8 (5): 362-371. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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