Edit |   |
---|---|
Antigenic Specificity | Synaptophysin, Mouse/Rat |
Clone | REA1143 |
Host Species | Recombinant Human |
Reactive Species | rat, mouse, human |
Isotype | IgG1 |
Format | fluorescein (FITC) conjugate |
Size | 200 µL |
Concentration | 1:50 |
Applications | MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Synaptophysin Antibody, anti-mouse/rat, FITC, REAfinity™. Clone REA1143 recognizes the rat and mouse Synaptophysin, an integral membrane glycoprotein also known as major synaptic vesicle protein p38. | Synaptophysin plays a role in the regulation of short-term and long-term synaptic plasticity and is involved in structural functions. It is detected in neuroendocrine cells and in neurons, which are involved in in synaptic transmission. Furthermore Synaptophysin is used as a tumor marker for different tumors which emerge from neural and neuroendocrine tissues. | Additional information: Clone REA1143 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | SYP |
Gene, Accession # | Gene ID: 20977, 24804 |
Catalog # | 130-119-724 |
Price | $187 |
Order / More Info | Synaptophysin, Mouse/Rat Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Sudhof, T.C. et al. (1987) A synaptic vesicle protein with a novel cytoplasmic domain and four transmembrane regions. Science 238 (4830): 1142-1144. | Bargou, R. C. and Leube, R. E. (1991) The synaptophysin-encoding gene in rat and man is specifically transcribed in neuroendocrine cells. Gene 99 (2): 197-204. |