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Antigenic Specificity | CD45RB, Human |
Clone | REA119 |
Host Species | Recombinant Human |
Reactive Species | human, nonhuman primate |
Isotype | IgG1 |
Format | PE-Vio 770 conjugate |
Size | 100 tests in 1 mL |
Concentration | 1:11 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD45RB Antibody, anti-human, PE-Vio® 770, REAfinity™. Clone REA119 recognizes CD45RB, which is a splice variant isoform of CD45, the leukocyte common antigen (LCA). CD45 is a haemopoietic cell specific protein tyrosine phosphatase, and regulates various signaling events through cytokine receptors and in response to cellular adhesion. Expression of CD45RB is found on T cell subset, B cells, monocytes/macrophages, granulocytes, and dendritic cells. | Additional information: Clone REA119 displays negligible binding to Fc receptors. | |
Immunogen | n/a |
Other Names | Ptprc, B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200 |
Gene, Accession # | Gene ID: 5788 |
Catalog # | 130-100-644 |
Price | $350 |
Order / More Info | CD45RB, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Parikh, K. et al. (2009) Extracellular ligation-dependent CD45RB enzymatic activity negatively regulates lipid raft signal transduction. Blood 113: 594-603. | Dianzani, U. et al. (1992) Isoform-specific associations of CD45 with accessory molecules in human T lymphocytes. Eur. J. Immunol. 22 (2): 365-371. |