ASGPR1, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | ASGPR1, Human |
| Clone | REA608 |
| Host Species | Recombinant Human |
| Reactive Species | human, rat |
| Isotype | IgG1 |
| Format | Vio Bright FITC conjugate |
| Size | 100 tests in 1 mL |
| Concentration | 1:11 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | ASGPR1 Antibody, anti-human, Vio® Bright FITC, REAfinity™. Clone REA608 recognizes the human and rat asialoglycoprotein receptor 1 (ASGPR1) antigen, a single-pass type II membrane protein, also known as C-type lectin domain family 4 member H1 (CLEC4H1) or hepatic lectin H1 (HL-1). ASGPR1 is the major subunit of the asialoglycoprotein receptor (ASGPR) and is specifically expressed on the sinusoidal and basolateral hepatocellular membranes, but not on the bile canalicular membrane. It plays a role in the clearance of desialylated proteins from the serum through endocytosis and lysosomal degradation. | Additional information: Clone REA608 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | Hepatic lectin, Asialoglycoprotein receptor 1, ASGP-R 1, C-type lectin domain family 4 member H1, Hepatic lectin H1, HL-1, ASGR1, CLEC4H1 |
| Gene, Accession # | Gene ID: 432 |
| Catalog # | 130-109-411 |
| Price | $395 |
| Order / More Info | ASGPR1, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Shi, B. et al. (2013) Expression of asialoglycoprotein receptor 1 in human hepatocellular carcinoma. J. Histochem. Cytochem. 61 (12): 901-909. | Rigopoulou, E. I. et al. (2012) Asialoglycoprotein receptor (ASGPR) as target autoantigen in liver autoimmunity: lost and found. Autoimmun Rev 12 (2): 260-269. | Yang, J. et al. (2006) Antisense oligonucleotides targeted against asialoglycoprotein receptor 1 block human hepatitis B virus replication. J. Viral Hepat. 13 (3): 158-165. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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