LYVE-1, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | LYVE-1, Human |
| Clone | REAL1161 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | n/a |
| Format | fluorescein (FITC) conjugate |
| Size | 200 µL |
| Concentration | n/a |
| Applications | MICS (MACSima Imaging Cyclic Staining), Immunohistochemistry, Immunofluorescence |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | LYVE-1 Antibody, anti-human, FITC, REAdye_lease™. Clone REAL1161 is an antibody fragment derived from the full LYVE-1 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL1161 recognizes the human LYVE-1 protein, also known as lymphatic vessel endothelial hyaluronic acid receptor 1, LYVE1, XLKD1 or CRSBP-1. LYVE-1 is a type I integral membrane glycoprotein, which is a lymph-specific receptor for hyaluronan and homologous to CD44. LYVE-1 is mainly expressed in endothelial cells lining lymphatic vessels, but also in normal hepatic blood sinusoidal endothelial cells. LYVE-1 is an indicator for human hepatocellular carcinoma. It is involved in lymphatic hyaluronan transport, in tumor metastasis and autocrine regulation of cell growth. Lyve-1 is expressed in liver cancer. | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675). | |
| Immunogen | n/a |
| Other Names | LYVE1, CRSBP-1, CRSBP1, HAR, XLKD1 |
| Gene, Accession # | n/a |
| Catalog # | 130-128-001 |
| Price | $385 |
| Order / More Info | LYVE-1, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Banerji, S. et al. (1999) LYVE-1, a new homologue of the CD44 glycoprotein, is a lymph-specific receptor for hyaluronan. J. Cell Biol. 144 (4): 789-801. | Mouta Carreira, C. et al. (2001) LYVE-1 is not restricted to the lymph vessels: expression in normal liver blood sinusoids and down-regulation in human liver cancer and cirrhosis. Cancer Res. 61 (22): 8079-8074. | Rinaldi, E. et al. (2018) LYVE-1 is 'on stage' now: an emerging player in dendritic cell docking to lymphatic endothelial cellsElena Rinaldi and Fulvio Baggicorresponding author. Cell. Mol. Immunol. 15 (7): 663-665. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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