CD334 (FGFR4), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD334 (FGFR4), Human |
| Clone | REA1243 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | PE-Vio 770 conjugate |
| Size | 30 tests in 60 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD334 (FGFR4) Antibody, anti-human, PE-Vio® 770, REAfinity™. Clone REA1243 recognizes the human CD334 (FGFR4) antigen, known as Fibroblast growth factor receptor 4, which is a member of the fibroblast growth factor receptor family. This cell surface tyrosine kinase is a high affinity receptor for both acidic and basic fibroblast growth factor. The binding of CD334 with the acidic fibroblast growth factors FGF2, FGF6, and FGF8, FGF19 and GFG1 induces mitogenesis and differentiation. CD334 is expressed in adrenal, lung, kidney, liver, pancreas, intestine, striated muscle and spleen tissues of human fetuses. A soluble-form splice variant of FGFR 4 was identified in human gastrointestinal epithelial cells and cancer cells. | Additional information: Clone REA1243 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | FGFR-4, FGFR4, TKF, FGF R4 |
| Gene, Accession # | Gene ID: 2264 |
| Catalog # | 130-124-926 |
| Price | $164 |
| Order / More Info | CD334 (FGFR4), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Partanan, J. et al. (1991) FGFR-4, a novel acidic fibroblast growth factor receptor with a distinct expression pattern. EMBO J. 10 (6): 1347-1354. | Takaishi, S. et al. (2000) Identification of a novel alternative splicing of human FGF receptor 4: soluble-form splice variant expressed in human gastrointestinal epithelial cells. Biochem. Biophys. Res. Commun. 267 (2): 658-662. | Ron, D. et al. (1993) Fibroblast growth factor receptor 4 is a high affinity receptor for both acidic and basic fibroblast growth factor but not for keratinocyte growth factor. J. Biol. Chem. 268 (8): 5388-5394. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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