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Antigenic Specificity | CD180 (RP105), Human |
Clone | MHR73-11 |
Host Species | Mouse |
Reactive Species | human, nonhuman primate |
Isotype | IgG1κ |
Format | fluorescein (FITC) conjugate |
Size | 100 tests in 1 mL |
Concentration | 1:11 |
Applications | Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD180 (RP105) Antibody, anti-human, FITC. The monoclonal antibody MHR73-11 recognizes human CD180, also known as RP105, which is a 105 kDa type 1 transmembrane protein of the toll-like receptor (TLR) family. The extracellular domain of CD180 is associated with MD-1, which forms the cell surface complex RP105/MD-1. Together with TLR4, it mediates B cell recognition and signaling of LPS. CD180 is expressed on mature B cells in mantle zones, on monocytes, macrophages, and dendritic cells. |
Immunogen | n/a |
Other Names | LY64, Ly78, RP105 |
Gene, Accession # | Gene ID: 4064 |
Catalog # | 130-098-484 |
Price | $264 |
Order / More Info | CD180 (RP105), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Miura, Y. et al. (1998) RP105 Is associated with MD-1 and transmits an activation signal in human B cells. Blood 92: 2815 - 2822. | Divanovic, S. et al. (2005) Negative regulation of Toll-like receptor 4 signaling by the Toll-like receptor homolog RP105. Nat Immunol 6 (6): 571-578. | Ogata, H. et al. (2000) The toll-like receptor protein Rp105 regulates lipopolysaccharide signaling in B cells. J. Exp. Med. 192: 23-30. |