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Antigenic Specificity | MHC Class II, Mouse |
Clone | REA813 |
Host Species | Recombinant Human |
Reactive Species | mouse |
Isotype | IgG1 |
Format | VioBlue conjugate |
Size | 150 µg in 1 mL |
Concentration | 1:50 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | MHC Class II Antibody, anti-mouse, VioBlue®, REAfinity™. Clone REA813 recognizes the MHC class II alloantigens I-Ab, I-Aq, I-Ad, I-Ed, and I-Ek that are expressed by most common inbred mouse strains, for example, C57BL/6, BALB/c, or 129/SvEv 1. MHC class II is expressed on antigen-presenting cells, such as dendritic cells, monocytes/macrophages, B cells in lymphoid and non-lymphoid tissue, thymic epithelial cells, and on subsets of hematopoietic progenitor cells in the bone marrow. | Additional information: Clone REA813 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | H2-AB1, Abeta, H-2Ab, H2-Ab, I-Abeta, IAb, Ia-2, Ia2, Rmcs1 |
Gene, Accession # | Gene ID: 14961 |
Catalog # | 130-112-237 |
Price | $465 |
Order / More Info | MHC Class II, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Bhattacharya, A. et al. (1981) A shared alloantigenic determinant on Ia antigens encoded by the I-A and I-E subregions: evidence for I region gene duplication. J Immunol 127 (6): 2488-2495. | Watts, C. (1997) Capture and processing of exogenous antigens for presentation on MHC molecules. Annu. Rev. Immunol. 15: 821-850. |