Edit |   |
---|---|
Antigenic Specificity | TCR Vβ3, Mouse |
Clone | REA646 |
Host Species | Recombinant Human |
Reactive Species | mouse |
Isotype | IgG1 |
Format | PE-Vio 770 conjugate |
Size | 9 µg in 300 µL |
Concentration | 1:10 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TCR Vβ3 Antibody, anti-mouse, PE-Vio® 770, REAfinity™. Clone REA646 recognizes the mouse V beta 3 T cell receptor (TCR Vβ3). The T cell receptor is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable α and β chains expressed as part of a complex with the invariant CD3 chain molecules. The α and β TCR chains are composed of constant and variable regions, each encoded by distinct gene segments. TCR Vβ3 is a variant of the TCR β chain and is expressed on T cells having the a, b, and c haplotype of the TCR β gene complex. | Additional information: Clone REA646 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | TCR Vb3, Gm2426, Tcrb-V16 |
Gene, Accession # | Gene ID: 100039790 |
Catalog # | 130-109-894 |
Price | $57 |
Order / More Info | TCR Vβ3, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Lee, J. S. et al. (2006) Antigen-specific expansion of TCR Vbeta3+ CD4+ T cells in the early stage of collagen-induced arthritis and its arthritogenic role in DBA/1J mice. J. Clin. Immunol. 26 (3): 204-212. | Fairchild, S. et al. (1992) Tcrb-V3+ T-cell deletion and a new mouse mammary tumor provirus, Mtv-44. Immunogenetics 36 (3): 189-194. | Tomonari, K. et al. (1992) Tcrb-V3+ T-cell deletion and a mouse mammary tumor provirus, Mtv-27. Immunogenetics 36 (5): 302-305. |