CD21/CD35, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD21/CD35, Mouse |
| Clone | REA800 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | phycoerythrin (PE) conjugate |
| Size | 30 µg in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD21/CD35 Antibody, anti-mouse, PE, REAfinity™. Clone REA800 recognizes an epitope shared by mouse CD21 and CD35, also known as CR2 and CR1. CD21 and CD35 are alternatively spliced transcripts from the Cr2 gene, which produce cell-surface proteins of 145 and 190 kDa, respectively. CD21 and CD35 are expressed on the majority of peripheral B lymphocytes, on the majority of resident peritoneal macrophages, on mast cells, activated granulocytes, and follicular dendritic cells. CD21 forms part of a signal transduction complex with CD19 and CD81, which are associated with the antigen receptor on B lymphocytes. | Additional information: Clone REA800 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | CR2, C3dR, C3b/C4b-R, CR1, EBV-R, Immune adherence receptor |
| Gene, Accession # | Gene ID: 12902 |
| Catalog # | 130-111-730 |
| Price | $67 |
| Order / More Info | CD21/CD35, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Kozono, Y. et al. (1998) Cross-linking CD21/CD35 or CD19 increases both B7-1 and B7-2 expression on murine splenic B cells. J Immunol 160 (4): 1565-1572. | Brockman, M. A. et al. (2006) Optimal long-term humoral responses to replication-defective herpes simplex virus require CD21/CD35 complement receptor expression on stromal cells. J. Virol. 80 (14): 7111-7117. | Roozendaal, R. et al. (2007) Complement receptors CD21 and CD35 in humoral immunity. Immunol. Rev. 219: 157-166. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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