CD18, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD18, Human |
| Clone | TS1/18 |
| Host Species | Mouse |
| Reactive Species | human, other |
| Isotype | IgG1κ |
| Format | PE-Vio 770 conjugate |
| Size | 30 tests in 300 µL |
| Concentration | 1:11 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD18 Antibody, anti-human, PE-Vio® 770. Clone TS1/18 reacts with CD18, a type I transmembrane protein with an approximate molecular weight of 90-95 kDa. It non-covalently associates with α subunits CD11a (αL), CD11b (αM), CD11c (αX), and CD11d (αD) to form functional integrins which are expressed on leucocytes. CD18 associated integrins bind several ligands including cell surface and extracellular matrix proteins and are involved in cell-cell and cell-extracellular matrix interactions, immune regulation, and immune tolerance. Leucocytes of patients lacking CD18 or expressing dysfunctional CD18 are defective in chemotaxis, phagocytosis, and homotypic aggregation. |
| Immunogen | n/a |
| Other Names | ITGB2, CD18, LAD, LCAMB, LFA-1, Mac-1 α, MF17, MFI7 |
| Gene, Accession # | n/a |
| Catalog # | 130-106-062 |
| Price | $162 |
| Order / More Info | CD18, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Tan, S. M. (2012) The leucocyte β2 (CD18) integrins: the structure, functional regulation and signalling properties. Biosci. Rep. 32 (3): 241-269. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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