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Antigenic Specificity | CD240DCE, Human |
Clone | REA327 |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | IgG1 |
Format | APC-Vio 770 conjugate |
Size | 100 tests in 200 µL |
Concentration | 1:50 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD240DCE Antibody, anti-human, APC-Vio® 770, REAfinity™. Clone REA327 recognizes the human CD240DCE antigens, multi-pass membrane proteins which are also known as blood group Rhesus (DCE) polypeptides. The Rhesus (Rh) blood group system is the most clinically significant blood group system after ABO. At present, the Rh blood group system consists of 50 defined blood-group antigens, among which the antigens D, C, and E are the most important. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic CD240D (RhD) protein on the surface of erythrocytes. Besides its role in blood transfusion, the Rh blood group system - specifically, the CD240D antigen - is used to determine the risk of hemolytic disease of the newborn as prevention is the best approach to the management of this condition. | Additional information: Clone REA327 displays negligible binding to Fc receptors. | |
Immunogen | n/a |
Other Names | RHCE, RHD, Rh polypeptide 2 (RhPII), Rhesus D antigen, Blood group Rh(CE) polypeptide (RHCE) |
Gene, Accession # | Gene ID: 6007, 6006 |
Catalog # | 130-129-775 |
Price | $400 |
Order / More Info | CD240DCE, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Smythe, J. S. et al. (1996) Expression of RHD and RHCE gene products using retroviral transduction of K562 cells establishes the molecular basis of Rh blood group antigens. Blood 87 (7): 2968-2973. | Wagner, F. F. et al. (2000) RHD gene deletion occurred in the Rhesus box. Blood 95 (12): 3662-3668. | Wagner, F. F. et al. (2004) Review: the molecular basis of the Rh blood group phenotypes. Immunohematology 20 (1): 23-36. |