CD253, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD253, Mouse |
| Clone | N2B2 |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgG2aκ |
| Format | allophycocyanin (APC) conjugate |
| Size | 30 µg in 1 mL |
| Concentration | 1:10 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD253 Antibody, anti-mouse, APC. Clone N2B2 reacts with murine CD253, a type 2 transmembrane protein, also known as TNF-related apoptosis-inducing ligand (TRAIL), APO-2 ligand (APO-2L), or TNF ligand superfamily member 10 (TNFSF10). CD253 is expressed on a variety of cells of the innate and adaptive immune system, including natural killer (NK) cells. Often expression is induced or upregulated upon activation. CD253 can trigger apoptosis through trimerization of death receptor DR5 (TRAILR). The N2B2 antibody is reported to block CD253-mediated NK cell cytotoxicity in vitro. |
| Immunogen | n/a |
| Other Names | TNFSF10, APO2L, Ly81, TL2, TRAIL |
| Gene, Accession # | Gene ID: 22035 |
| Catalog # | 130-102-510 |
| Price | $93 |
| Order / More Info | CD253, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | n/a |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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