CD278 (ICOS), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD278 (ICOS), Mouse |
| Clone | 7E.17G9 |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgG2bκ |
| Format | PerCP-Vio 700 conjugate |
| Size | 9 µg in 300 µL |
| Concentration | 1:10 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD278 (ICOS) Antibody, anti-mouse, PerCP-Vio® 700. Clone 7E.17G9 reacts with CD278, the inducible co-stimulatory molecule (ICOS), a 47-57 kDa homodimeric glycoprotein of the CD28 family. Directly ex vivo, CD278 is expressed only by a small subset of T cells, including follicular B helper T cells (TFH) and regulatory T cells. However, CD278 is strongly up-regulated on the surface following T cell activation. Upon binding to its ligand (ICOSL), CD278 initiates a multitude of events, which modulate many different aspects of T cell-mediated immune responses. Besides regulating differentiation and activation of effector as well as regulatory CD4+ T cells, ICOS also plays a role in germinal center formation and isotype switching. |
| Immunogen | n/a |
| Other Names | ICOS, AILIM, CCLP, CRP-1, H4, Ly115 |
| Gene, Accession # | Gene ID: 54167 |
| Catalog # | 130-105-194 |
| Price | $57 |
| Order / More Info | CD278 (ICOS), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | n/a |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
Profile of MILTENYI BIOTEC B.V. & Co. KG